Day: September 14, 2022

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Sabin Receives Additional $21.8 Million From BARDA to Advance Marburg Vaccine

WASHINGTON, Sept. 14, 2022 (GLOBE NEWSWIRE) — The Sabin Vaccine Institute today announced it is receiving an additional $21.8 million under an existing contract with the Biomedical Advanced Research and Development Authority (BARDA), part of the Administration for Strategic Preparedness and Response at the U.S. Department of Health and Human Services. These funds advance development of a vaccine against Marburg virus disease, a virus that is related to Ebola Zaire which killed 2200 people during the last major outbreak that ended in 2020.

The Sabin Marburg vaccine is the only candidate currently slated for a Phase 2 clinical trial. Marburg is among the world’s deadliest viruses, resulting in the death of approximately half the people the virus infects. Currently, there are no approved vaccines or treatments for the disease. As recently as July this year, two people in Ghana died after being infected with Marburg virus, reinforcing the urgent need for medical therapies.

The latest tranche of funds enables Sabin to conduct a randomized, blinded, placebo-controlled clinical trial among adults in the U.S. to further evaluate the safety and the efficacy of the Marburg vaccine candidate and advance non-clinical vaccine dosing studies. The Phase 2 clinical trial in the U.S. will begin after Sabin has initiated a same-stage trial in Africa, currently scheduled for 2023. Sabin will also undertake a non-clinical study on the vaccine candidate during this phase.

“Beginning Phase 2 clinical trials for the Marburg vaccine is a pivotal milestone for us and we appreciate BARDA’s continued confidence in our work and support for this critical next step,” says Sabin Chief Executive Officer Amy Finan. “Vaccines remain our best bet against death and disability from deadly viruses. I am hopeful that in the years ahead, we can offer this life-saving vaccine to every person who needs it.”

In 2019, BARDA awarded Sabin a multi-year contract valued at $128 million to further the development of vaccines against two lethal viruses: Marburg and Ebola Sudan. With BARDA now exercising the latest option of that contract, Sabin’s Ebola and Marburg Research & Development program, to date, has been awarded $98.6 million.

BARDA is part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services. This project has been funded in whole or in part with federal funds from the Department of Health and Human Services; Administration for Strategic Preparedness and Response; Biomedical Advanced Research and Development Authority, under contract number 75A50119C000555.

Learn more about Sabin’s Marburg and Ebola Sudan Program.

About the Sabin Vaccine Institute

The Sabin Vaccine Institute is a leading advocate for expanding vaccine access and uptake globally, advancing vaccine research and development, and amplifying vaccine knowledge and innovation. Unlocking the potential of vaccines through partnership, Sabin has built a robust ecosystem of funders, innovators, implementers, practitioners, policy makers and public stakeholders to advance its vision of a future free from preventable diseases. As a non-profit with more than two decades of experience, Sabin is committed to finding solutions that last and extending the full benefits of vaccines to all people, regardless of who they are or where they live. At Sabin, we believe in the power of vaccines to change the world. For more information, visit www.sabin.org and follow us on Twitter, @SabinVaccine.

About Ebola Sudan and Marburg

Ebola Sudan and Marburg are members of the filovirus family. Both can cause severe hemorrhagic fever in humans and nonhuman primates. No therapeutic treatment of the hemorrhagic fevers caused by filoviruses has been licensed to date. Marburg and Ebola viruses are transmitted to humans by infected animals, particularly fruit bats. Once a human is infected, the virus can spread to others through close personal contact or contact with bodily fluids. Isolation of infected people is currently the centerpiece of filovirus control.

Marburg was the first filovirus to be recognized in 1967 when outbreaks of hemorrhagic fever were reported in a few Europe-based laboratories including in the town of Marburg, Germany. Ebola was identified in 1976 when two simultaneous outbreaks occurred in northern Zaire (now the DRC) in a village near the Ebola River and southern Sudan. The outbreaks involved what eventually proved to be two different species of Ebola virus; both were named after the nations in which they were discovered.

Media contact:

Rajee Suri
press@sabin.org

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Radware Launches New Cloud Security Center in the United Arab Emirates

Responds to regional demand for low latency performance and complies with offshore data routing requirements

MAHWAH, N.J., Sept. 14, 2022 (GLOBE NEWSWIRE) — Radware® (NASDAQ: RDWR), a leading provider of cyber security and application delivery solutions, announced the launch of a new cloud security center in the United Arab Emirates. Located in Dubai, the facility will reduce latency for in-region traffic and offer customers faster mitigation response times against denial-of-service attacks, web application attacks, malicious bot traffic, and attacks on APIs. It will also mitigate compliance processes involved in offshore routing.

The Dubai addition complements Radware’s existing cloud security network. Today, the network includes over 10Tbps of mitigation capacity across more than 50 security centers located around the globe.

“As part of our strategic cloud services initiative, we continue to accelerate cloud innovation to provide our customers with the highest level of cyber security services,” said Haim Zelikovsky, vice president of cloud security services for Radware. “This includes increasing the fighting capacity of our cloud infrastructure to help our customers manage the increasing complexity and sheer volume of cyberattacks with as little disruption as possible.”

According to Radware’s First Half 2022 Global Threat Analysis Report, the first six months of 2022 saw a dramatic increase in cyberattacks across the globe. The number of DDoS attacks climbed 203% and malicious web application transactions grew by 38% compared to the same period last year.

“The new site in Dubai fills a growing demand for a local security presence that can deliver rapid response times with accuracy for organizations in the public and private sector,” said Nikhil Karan Taneja, Radware’s vice president and managing director for India, the Middle East, and South Asia. “The launch of the center underscores our ongoing commitment to delivering state-of-the-art cyber protection and scaling our capacity in a way that will benefit the whole region.”

About Radware
Radware® (NASDAQ: RDWR) is a global leader of cyber security and application delivery solutions for physical, cloud, and software defined data centers. Its award-winning solutions portfolio secures the digital experience by providing infrastructure, application, and corporate IT protection, and availability services to enterprises globally. Radware’s solutions empower enterprise and carrier customers worldwide to adapt to market challenges quickly, maintain business continuity, and achieve maximum productivity while keeping costs down. For more information, please visit the Radware website.

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Media Contact:
Gerri Dyrek
Radware
Gerri.Dyrek@radware.com